Innovate Less Lethal to De-Escalate Tax Modernization Act

House Bill

H.R. 4242

119th Congress

Innovate Less Lethal to De-Escalate Tax Modernization Act

In Committee

Introduced:Jul 21, 2025

Primary Sponsor

Dan Crenshaw

Representative

Republican

TX-2

Cosponsors

2

Quick Stats

Policy Area

Health

Summary

This bill requires the FDA to provide guidance on conducting clinical trials for psychedelic-assisted therapy, which uses substances like psilocybin or MDMA along with therapy to treat mental health conditions.

Latest Action

Referred to the Subcommittee on Health.

SponsorDan Crenshaw (R-TX)

Introduced7/21/2025

StatusReferred to the House Committee on Ways and Means.

ChamberHouse

Data from Congress.gov

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Vote Prediction

Innovate Less Lethal to De-Escalate Tax Modernization Act

This bill requires the FDA to provide guidance on conducting clinical trials for psychedelic-assisted therapy, which uses substances like psilocybin or MDMA along with therapy to treat mental health conditions.

Community Breakdown

Pass

0%

Fail

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0 predictions

This bill requires the FDA to provide guidance on conducting clinical trials for psychedelic-assisted therapy, which uses substances like psilocybin or MDMA along with therapy to treat mental health conditions.

Bill Number: 4242
Sponsor: Dan Crenshaw (R-TX)
Introduced: 7/21/2025
Status: Referred to the House Committee on Ways and Means.
Policy Area: Health

Data from Congress.gov

AI-generated summary

Fact Sheet

Title: Innovate Less Lethal to De-Escalate Tax Modernization Act
Bill Number: 4242
Sponsor: Dan Crenshaw (R-TX)
Status: Referred to the House Committee on Ways and Means.
Introduced: 7/21/2025
Summary: This bill requires the FDA to provide guidance on conducting clinical trials for psychedelic-assisted therapy, which uses substances like psilocybin or MDMA along with therapy to treat mental health conditions.

Data from Congress.gov

AI Summary

Plain-English explanation of this bill

This bill requires the FDA to provide guidance on conducting clinical trials for psychedelic-assisted therapy, which uses substances like psilocybin or MDMA along with therapy to treat mental health conditions.

Last updated: 12/30/2025

Official Summary

Congressional Research Service summary

<p>This bill requires the Food and Drug Administration (FDA) to issue guidance on considerations for conducting clinical trials for psychedelic assisted therapy, including how to request support from the FDA for related investigational use exemptions.</p>

Key Points

Main provisions of the bill

The bill directs the FDA to issue guidance on how to request support for investigational use of psychedelic substances in clinical trials.
The guidance would cover considerations for designing and running clinical trials to evaluate the safety and effectiveness of psychedelic-assisted therapy.
The goal is to make it easier for researchers to study the potential medical uses of psychedelics under FDA oversight.

How This Impacts Americans

Potential effects on citizens and communities

If passed, this bill could accelerate research into using psychedelics as part of mental health treatments. It would primarily impact researchers, clinicians, and patients interested in exploring the therapeutic potential of substances like psilocybin or MDMA when combined with therapy. Ultimately, it could lead to new approved treatments for conditions like depression, PTSD, and addiction if the research proves successful.

Policy Areas

Primary Policy Area

Health

Related Subjects

Administrative law and regulatory procedures

Alternative treatments

Department of Health and Human Services

Drug therapy

Drug, alcohol, tobacco use

Medical research

Scope & Jurisdiction

Jurisdiction Level

federal

Congressional Session

119th Congress

Citation Reference

4242, 119th Congress (2025). "Innovate Less Lethal to De-Escalate Tax Modernization Act". Source: Voter's Right Platform. https://votersright.org/bills/118-hr-4242